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2 cards from this section. Quick, good the night before a test.
Define nitrile and give an example.
Nitriles have a carbon triple bond to nitrogen.
What is the formula for the reduction of a nitrile?
Focus on the change from the cyano group to the amine.
What does RCN reduce to when hydrogen and a catalyst are applied?
Think about the functional group change.
True or False: Amides can be reduced to primary amines.
Recall the reduction reaction for amides.
Design a synthetic pathway starting from an alkyne, detailing how you would produce an amine through the reductions of both a nitrile and an amide.
Think about the functional group changes at each stage.
Explain how you would conduct a reduction experiment of a nitrile in the lab, detailing the methods and safety precautions necessary.
Consider the equipment and setup required for hydrogenation.
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