Practice Sequence Alignment (4.2.2) - Chapter 4: Bioinformatics

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6 sample questions

Question 1.
What is the purpose of sequence alignment?
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Think about why comparing DNA is important.
Question 2.
What does BLAST stand for?
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It's a tool for searching similarities.
3Question 3.
What is the main purpose of sequence alignment?
- To increase the size of the database
- To compare sequences
- To create new genetic data
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Think about the function of comparing DNA or protein sequences.
4Question 4.
True or False: BLAST is an example of a sequence alignment tool.
- True
- False
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Recall what BLAST is used for.
Question 5.
You have two DNA sequences: Sequence A (AGCTTAGC) and Sequence B (AGTTGAC). Use global alignment principles to assess if these sequences share a homologous region and explain your reasoning.
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Consider common bases and where they align.
Question 6.
A scientist uses MSA for three protein sequences (P1, P2, P3) and finds a conserved region. Based on this information, how might this influence therapeutic approaches for diseases?
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Think about how evolutionary conservation aids in understanding function.

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