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3 cards from this section. Quick, good the night before a test.
Define a nucleophile.
Think about what nucleophiles do in a reaction.
What is a substitution reaction?
It involves switching one part for another.
What type of reaction involves a nucleophile replacing a leaving group?
Consider the definition of a nucleophile.
True or False: SN2 reactions lead to racemization.
Think about what happens to the stereochemistry in SN2.
Consider a reaction where 3-chloro-2-methylpentane undergoes an SN2 substitution reaction with hydroxide. What products can be expected, and what is the stereochemistry of the product?
Don’t forget to apply the backside attack in SN2!
Write a detailed mechanistic pathway for the oxidation of a primary alcohol to a carboxylic acid. What reagents are needed and what steps are involved?
Focus on the specifics of how primary alcohols oxidize through intermediates.
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