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2 cards from this section. Quick, good the night before a test.
What is phthalimide used for in Gabriel synthesis?
Think about its role in the reaction mechanism.
What type of amine is produced by Gabriel synthesis?
Recall how many hydrogens are associated with nitrogen in primary amines.
What type of amines does the Gabriel synthesis form?
Remember the definition of primary amines.
True or False: Gabriel synthesis can produce aromatic primary amines.
Think about the structure of aryl halides.
Design a synthetic route using Gabriel phthalimide synthesis to obtain propylamine starting from phthalimide.
Follow the steps we discussed in class!
Compare the yields of primary amines produced from Gabriel synthesis versus direct reduction of nitro compounds and explain the advantages.
Consider the specificity of the Gabriel method!
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